I have two properties.
How do I set two emails that will have a 2 different "From" so the guests know that I am responding with my business email.
Is that possible? Or we only have one email account that we use to respond to the guest regardless of what property it is.
By default, all email will use your account email as the reply to.
If you want, you could go into the email template settings and change the FROM to use a different email. Are you looking to have a different FROM email per property? You can accomplish that using custom fields with a different value set for each property.
Normally, though, I find that the single reply to is better so folks don't get confused if they are inquiring for multiple properties etc.
If you have your own domain name with email configured, we can actually set up to send email directly from that address -- let me know and I can walk you through the setup steps for that.